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  1. Jun 23, 2023 · Bullous pemphigoid is an autoimmune cutaneous blistering disease characterized by autoantibody deposition at the epithelial basement membrane zone. The disorder most frequently affects older adults and classically presents with generalized, pruritic, urticarial plaques and tense, subepithelial blisters ( picture 1A-D ).

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  3. Apr 15, 2022 · The 11 factors of age, sex, disease severity, general condition, bullous pemphigoid 180 antibody, IIF, dementia, stroke, hypertension, heart disease and diabetes, which may affect the prognosis of patients with bullous pemphigoid, were assessed by meta-analysis.

    • 10.1371/journal.pone.0264705
    • 2022
    • PLoS One. 2022; 17(4): e0264705.
    • What Are The Symptoms of Bullous Pemphigoid?
    • What Causes Bullous Pemphigoid?
    • Do Certain Foods Trigger Bullous Pemphigoid?
    • Is Bullous Pemphigoid Contagious?

    Bullous pemphigoid appears as itchy welts that look like hives or multiple, itchy blisters (bullae). It most commonly appears on your: 1. Arms. 2. Legs. 3. Abdomen. 4. Groin. 5. Mouth. The blisters typically appear along the creases of your skin. They usually aren’t painful, but they may break open and become a painful sore or ulcer. The fluid insi...

    Bullous pemphigoid is an autoimmune disease. Healthcare providers and medical researchers aren’t sure why your immune system responds this way. Certain medications may trigger bullous pemphigoid, including the diabetes medication alogliptin. Ultraviolet (UV) light and ionizing radiation may also trigger or aggravate bullous pemphigoid.

    Healthcare providers and medical researchers aren’t sure if diet affects bullous pemphigoid. Some people have reported their bullous pemphigoid improved or went away after eliminating certain foods from their diet. However, there’s currently no good scientific evidence to support that certain foods trigger bullous pemphigoid. If you have bullous pe...

    No, bullous pemphigoid isn’t contagious. You can’t spread bullous pemphigoid to another person through skin-to-skin contact.

  4. Sep 27, 2022 · Bullous pemphigoid often goes away on its own in a few months, but may take as many as five years to resolve. Treatment usually helps heal the blisters and ease any itching. It may include corticosteroid medications, such as prednisone, and other drugs that suppress the immune system.

  5. Mar 2, 2023 · Histopathology, direct and indirect immunofluorescence studies, salt-split skin, and ELISA testing may be necessary if the diagnosis of bullous pemphigoid is questioned. Prognosis Bullous pemphigoid typically resolves spontaneously in a few months but can remain for up to 5 years.

    • Dana Baigrie, Vinod Nookala
    • 2023/03/02
  6. For bullous pemphigoid, some basic questions to ask your doctor include: What's the most likely cause of my symptoms? Are there other possible causes? Do I need any tests? How long will these skin changes last? What treatments are available, and which do you recommend? What side effects can I expect from treatment? What to expect from your doctor

  7. Prognosis |. Key Points. Bullous pemphigoid is a chronic autoimmune skin disorder resulting in generalized, pruritic, bullous lesions in older adults. Mucous membrane involvement is rare. Diagnosis is by skin biopsy and immunofluorescence testing of skin and serum. Topical and systemic corticosteroids are used initially.

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