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Hair cells are the sensory receptors of both the auditory system and the vestibular system in the ears of all vertebrates, and in the lateral line organ of fishes. Through mechanotransduction, hair cells detect movement in their environment. [1]
Apr 19, 2023 · The researchers then combined the chemical compounds and siRNA molecules into a drug-like cocktail. They delivered it to the inner ear of a normal adult mouse with damaged hair cells — an important distinction, as wild-type, non-transgenic mice would be more translatable to humans.
Oct 21, 2022 · The inner hair cells are most responsive to louder sounds; the outer hair cells are most responsive to softer sounds. Each hair cell also has a connection to the hearing nerve, but the inner hair cell is most responsible for sending sound through the hearing nerve to the brain.
Jun 18, 2018 · Sensory hair cells are specialized secondary sensory cells that mediate our senses of hearing, balance, linear acceleration, and angular acceleration (head rotation).
May 10, 2024 · The cochlea is a fluid-filled, snail-like structure within a cavity in the inner ear. It plays a vital role in the function of hearing rather than simply being another component of the skeletal system. The cochlea contains hair cells that convert sound waves into electrical impulses that are carried along the auditory nerve to the brain.
Sensory hair cells of the inner ear are exposed to continuous mechanical stress, causing damage over time. The maintenance of hair cells is further challenged by damage from a variety of other ototoxic factors, including loud noise, aging, genetic defects, and ototoxic drugs.
The cochlear hair cells in humans consist of one row of inner hair cells and three rows of outer hair cells (see Figure 13.4). The inner hair cells are the actual sensory receptors, and 95% of the fibers of the auditory nerve that project to the brain arise from this subpopulation.
