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  1. Feb 1, 2024 · Infantile spasms is a seizure disorder that was first described by William West in 1841 and has been referred to as West syndrome. The disorder mainly affects those in their first year of life. The spasms present with characteristic EEG changes known as hypsarrhythmia and a strong association with developmental delay or regression. [1] .

  2. Infantile spasms are a specific type of seizure that begin in the first one to two years of life. Infantile spasms can be associated with a developmental regression (a loss of developmental milestones) and a highly irregular pattern of brain electrical activity, called hypsarrhythmia.

  3. Aug 10, 2023 · Infantile spasms represent an age-specific epileptic disorder of infancy and early childhood. Children with infantile spasms typically exhibit epileptic spasms along with the electroencephalographic (EEG) pattern known as hypsarhythmia.

  4. Mar 9, 2022 · Infantile spasms look like brief tensing or jerking spells that involve your baby’s abdomen (belly), head, neck, arms and/or legs. The spasms last for one to two seconds and usually happen one after another (in a series or cluster) every five to 10 seconds.

  5. Jul 19, 2024 · A specific brain wave pattern on electroencephalography (EEG) testing called hypsarrhythmia. The seizures often look like a sudden bending forward of the body with stiffening of the arms and legs lasting for one to two seconds; some children arch their backs as they extend their arms and legs.

  6. Jan 6, 2020 · Schematic showing characteristic electroencephalogram (EEG) findings in infantile spasms. Top trace: Hypsarrhythmia (interictal) consists of chaotic, high-voltage irregular slow waves (delta range, δ, <3 Hz) with superimposed sharp waves and spikes. Lightning bolt indicates onset of a clinical spasm.

  7. Mar 23, 2023 · Infantile spasms are an age-specific epileptic disorder of infancy and early childhood. Children with infantile spasms typically exhibit epileptic spasms along with the electroencephalographic (EEG) pattern known as hypsarhythmia.

  8. The associations between hypsarrhythmia at onset of infantile spasms and categorical variables such as sex, preexisting epilepsy, preexisting developmental delay, etiology, and age at onset (<3 months vs. ≥3 months) were assessed using chi-square analysis.

  9. Jan 11, 2019 · West syndrome is a severe epilepsy syndrome composed of the triad of infantile spasms, an interictal electroencephalogram pattern termed hypsarrhythmia, and intellectual disability.

  10. Doctors often confirm the diagnosis of infantile spasms with an electroencephalogram (EEG) test. An EEG shows a specific type of abnormal chaotic brainwave pattern called hypsarrhythmia. Infantile Spasm Causes and Risk Factors. Doctors associate more than 200 different health conditions as possible causes of IS.

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