Search results
Medium spiny neurons
- Cell types: Neurons in the nucleus accumbens are mostly medium spiny neurons (MSNs) containing mainly D1-type (i.e., DRD1 and DRD5) or D2-type (i.e., DRD2, DRD3, and DRD4) dopamine receptors.
en.wikipedia.org › wiki › Nucleus_accumbens
People also ask
What type of neuron is in the nucleus accumbens?
Which neurotransmitters are found in the nucleus accumbens core?
What are the two components of the nucleus accumbens?
Cell types: Neurons in the nucleus accumbens are mostly medium spiny neurons (MSNs) containing mainly D1-type (i.e., DRD1 and DRD5) or D2-type (i.e., DRD2, DRD3, and DRD4) dopamine receptors. A subpopulation of MSNs contain both D1-type and D2-type receptors, with approximately 40% of striatal MSNs expressing both DRD1 and DRD2 mRNA.
- NAc or NAcc
- Nucleus accumbens shell, Nucleus accumbens core
- nucleus accumbens septi
Oct 30, 2023 · The nucleus accumbens is part of a large group of subcortical nuclei collectively called the basal ganglia (basal nuclei). It lies in the rostral cerebral hemisphere, in the ventral forebrain. It was formerly called nucleus accumbens septi due to its close relation to the base of septum pellucidum.
- Medical Content
- 22 min
Feb 4, 2020 · Within this circuit, two distinct nucleus accumbens (NAc) output neuron types, dopamine D1 or D2 receptor-expressing neurons, dynamically control the flow of information through basal ganglia...
- Takatoshi Hikida, Shuhei Yao, Tom Macpherson, Tom Macpherson, Ayumi Fukakusa, Makiko Morita, Makiko ...
- 2020
We classified neurons in the human nucleus accumbens according to their morphology and size into four types: type I--fusiform neurons; type II--fusiform neurons with lateral dendrite, arising from a part of the cell body; type III--pyramidal-like neuron; type IV--multipolar neuron.
- Maja Sazdanovic, Predrag Sazdanovic, Ivana Zivanovic-Macuzic, Vladimir Jakovljevic, Dejan Jeremic, A...
- 2011
Oct 18, 2021 · The nucleus accumbens (NAc) plays an important role in regulating multiple behaviors, and its dysfunction has been linked to many neural disorders. However, the molecular, cellular and anatomic...
- Renchao Chen, Renchao Chen, Timothy R Blosser, Timothy R Blosser, Mohamed N Djekidel, Mohamed N Djek...
- 2021
Jul 1, 2020 · Using several in vivo mouse models, we show that newborn neurons integrate into preexisting circuits in the NAc where they mature as medium spiny neurons (MSNs), i.e., a type of projection...
Mar 19, 2015 · The nucleus accumbens (NAc) is a major component of the ventral striatum and has long been thought to be a key structure involved in mediating motivational and emotional processes, the limbic-motor interface, and the effects of certain psychoactive drugs.
