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  1. Lymphadenopathy or adenopathy is a disease of the lymph nodes, in which they are abnormal in size or consistency. Lymphadenopathy of an inflammatory type (the most common type) is lymphadenitis, [1] producing swollen or enlarged lymph nodes.

  2. Generalized lymphadenopathy is swollen lymph glands in many areas of the body. Usually this is in response to a body-wide infectious disease such as influenza and will go away once the person has recovered, but sometimes it can persist long-term, even when there is no obvious cause of disease.

    • Overview
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    Cervical lymphadenopathy refers to lymphadenopathy of the cervical lymph nodes. The term lymphadenopathy strictly speaking refers to disease of the lymph nodes, though it is often used to describe the enlargement of the lymph nodes. Similarly, the term lymphadenitis refers to inflammation of a lymph node, but often it is used as a synonym of lympha...

    Cervical lymphadenopathy can be thought of as local where only the cervical lymph nodes are affected, or general where all the lymph nodes of the body are affected.

    Lymph nodes may become enlarged in malignant disease. This cervical lymphadenopathy may be reactive or metastatic. Alternatively, enlarged lymph nodes may represent a primary malignancy of the lymphatic system itself, such as lymphoma, lymphocytic leukemia, Lymphadenopathy that l

    In possible malignancy, it is routine to perform a throat examination including mirror and/or endoscopy. On ultrasound, B-mode imaging depicts lymph node morphology, whilst power Doppler can assess the vascular pattern. B-mode imaging features that can distinguish metastasis and lymphoma include size, shape, calcification, loss of hilar architectur...

  3. Inguinal lymphadenopathy causes swollen lymph nodes in the groin area. It can be a symptom of infective or neoplastic processes. Infective aetiologies include Tuberculosis, HIV, non-specific or reactive lymphadenopathy to recent lower limb infection or groin infections.

  4. Mediastinal lymphadenopathy or mediastinal adenopathy is an enlargement of the mediastinal lymph nodes . Causes There are many possible causes of mediastinal lymphadenopathy, including: Tuberculosis Sarcoidosis Lung cancer / oesophageal cancer Lymphangitis carcinomatosa Cystic fibrosis Histoplasmosis Acute lymphoblastic leukemia Coccidioidomycosis

  5. Dermatopathic lymphadenopathy is diagnosed by a lymph node biopsy. It has a characteristic pattern of histomorphology and immunohistochemical staining : Paracortical histiocytosis. Melanin-laden macrophages. Eosinophils. Plasma cells (medulla of lymph node)

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