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What causes morbilliform drug eruption? Morbilliform drug eruption is a form of allergic reaction. It is mediated by cytotoxic T-cells and classified as a Type IV immune reaction. The target of attack may be drug, a metabolite of the drug, or a protein bonded to the drug. Inflammation follows the release of cytokines and other effector immune ...
Jan 12, 2023 · Exanthematous (maculopapular) drug eruption, also called morbilliform (measles-like) drug-induced exanthem, is the most common drug hypersensitivity reaction [ 1,2 ]. It is characterized by a disseminated, and occasionally generalized, symmetric eruption of erythematous macules and/or papules ( picture 1A-B) that occur approximately one to two ...
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Mar 13, 2019 · The onset of a morbilliform eruption (MDE; also known as exanthematous or maculopapular drug eruption) typically occurs within 7 to 10 days after the initiation of the culprit drug. Occasionally a 14-day window has been noted. On rechallenge with a drug that the patient has been sensitized to in the past, the eruption may occur within 24 hours.
Mar 4, 2022 · Morbilliform eruptions in the hospitalized child. The ability to accurately diagnose a child with a new-onset eruption in a timely manner is a fundamental skill for the dermatology consultant. Morbilliform eruptions inspire a broad and varied differential spanning across inflammatory and infectious categories.
- 10.1016/j.det.2021.12.006
- 2022/04
- Dermatol Clin. 2022 Apr; 40(2): 191-202.
Morbilliform drug eruption, also called “exanthematous” or “maculopapular drug eruption,” is the most common form of cutaneous drug eruption, accounting for more than 80% of drug eruptions. The term “morbilliform” is often used to describe this condition because the morphology and distribution of the rash looks similar to those of ...
Apr 10, 2023 · Exanthematous eruptions, also described as morbilliform or erythematous maculopapular eruptions, are the most common type of drug reaction, accounting for approximately 40% of all reactions. The rash develops one day to three weeks after the offending drug is first given, although the timing can differ if previously sensitized.
