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  1. What causes morbilliform drug eruption? Morbilliform drug eruption is a form of allergic reaction. It is mediated by cytotoxic T-cells and classified as a Type IV immune reaction. The target of attack may be drug, a metabolite of the drug, or a protein bonded to the drug. Inflammation follows the release of cytokines and other effector immune ...

  2. Jan 12, 2023 · Exanthematous (maculopapular) drug eruption, also called morbilliform (measles-like) drug-induced exanthem, is the most common drug hypersensitivity reaction [ 1,2 ]. It is characterized by a disseminated, and occasionally generalized, symmetric eruption of erythematous macules and/or papules ( picture 1A-B) that occur approximately one to two ...

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  4. Mar 13, 2019 · The onset of a morbilliform eruption (MDE; also known as exanthematous or maculopapular drug eruption) typically occurs within 7 to 10 days after the initiation of the culprit drug. Occasionally a 14-day window has been noted. On rechallenge with a drug that the patient has been sensitized to in the past, the eruption may occur within 24 hours.

  5. Morbilliform drug eruption, also called “exanthematous” or “maculopapular drug eruption,” is the most common form of cutaneous drug eruption, accounting for more than 80% of drug eruptions. The term “morbilliform” is often used to describe this condition because the morphology and distribution of the rash looks similar to those of ...

  6. Mar 4, 2022 · Morbilliform eruptions in the hospitalized child. The ability to accurately diagnose a child with a new-onset eruption in a timely manner is a fundamental skill for the dermatology consultant. Morbilliform eruptions inspire a broad and varied differential spanning across inflammatory and infectious categories.

    • 10.1016/j.det.2021.12.006
    • 2022/04
    • Dermatol Clin. 2022 Apr; 40(2): 191-202.
  7. Apr 10, 2023 · Exanthematous eruptions, also described as morbilliform or ery­thematous maculopapular eruptions, are the most common type of drug reaction, accounting for approximately 40% of all reactions. The rash develops one day to three weeks after the offending drug is first given, although the timing can differ if previously sensitized.

  8. Jun 28, 2012 · Most rashes due to medications are self-limited and only mildly symptomatic. The majority of skin events attributed to drugs are either exanthematous (maculopapular or morbilliform) eruptions (>80 ...

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