2010
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César Milstein was awarded the 1984 Nobel Prize in Physiology or Medicine jointly with his former postdoctoral fellow Georges J. F. Köhler (AAI '85) and theoretician Niels Jerne (AAI '73). Milstein and Köhler won the prize for developing the hybridoma method of producing monoclonal antibodies.
Mar 27, 2002 · César Milstein was one of the best-loved and most important scientists of the 20th century. He was part of the tradition of assimilating foreign genius into the British academic community and his achievements vindicate the policy of identifying and supporting research talent with long-term funding.
Showing César Milstein's notebooks and writings for the first time this exhibition explores the development of the first monoclonal antibodies.
6 days ago · Overview. César Milstein. (1927—2002) molecular biologist and immunologist. Quick Reference. (1927–2002) British molecular biologist. Milstein was born at Bahia Blanca in Argentina and attended the University of Buenos Aires, receiving his degree in 1952 and his doctorate in 1957. Three years later he was granted a PhD by Cambridge University.
Milstein, César, (8 Oct. 1927–24 March 2002), Scientific Staff of Medical Research Council, 1963–95; Fellow, Darwin College, University of Cambridge, 1981–95, Hon. Fellow, 2002; Joint Head, Division of Protein and Nucleic Acid Chemistry, 1981–93, Deputy Director, 1988–95, MRC Laboratory of Molecular Biology in Who Was Who
He focused on antibodies, the proteins produced by mature B lymphocytes (plasma cells) as part of the immune response. Milstein used myeloma cells, cancerous forms of plasma cells that multiply indefinitely, to study somatic hypermutation and the mechanism by which antibody diversity is generated.
Documentary. César Milstein describes how, while sitting in a meeting at his work at the MRC Laboratory of Molecular Biology, they were suddenly interrupted and he was informed that he had been awarded the Nobel Prize in Physiology or Medicine 1984. To cite this section. MLA style: César Milstein – Documentary.
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