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  1. Definition of lethal in the Definitions.net dictionary. Meaning of lethal. What does lethal mean? Information and translations of lethal in the most comprehensive ...

  2. Lethal Dose 50 (LD50 ) A single dose of a material which on the basis of laboratory tests is expected to kill 50% of a group of test animals. The LD50 dose is usually expressed as milligrams or grams of material per kilogram of animal body weight (mg/kg or g/kg). Importance: Both are measures of the toxicity of a substance. Go to Process Safety ...

  3. 4 days ago · LD stands for "Lethal Dose". LD 50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals. The LD 50 is one way to measure the short-term poisoning potential (acute toxicity) of a material. Toxicologists can use many kinds of animals but most often testing is done with rats and mice.

  4. lethal dose: [ dōs ] the quantity to be administered at one time, as a specified amount of medication or a given quantity of radiation. absorbed dose that amount of energy from ionizing radiations absorbed per unit mass of matter, expressed in rads. air dose the intensity of an x-ray or gamma-ray beam in air, expressed in roentgens. booster ...

  5. Infectious dose and transmission. An important aspect of Shigella pathogenesis is the extremely low ID 50, i.e. the experimentally determined oral dose required to cause disease in 50% of volunteers challenged with a virulent strain of the organism. The ID 50 for S. flexneri, S. sonnei, and S. dysenteriae is approximately 5,000 organisms.

  6. 50 test) are designed to determine the mean lethal dose of the test substance. The ... The Agency does not recommend that petitioners determine the median lethal dose (or LD 50) for direct ...

  7. ED 50. The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy ...

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