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  1. Mar 26, 2024 · Diphenhydramine is an FDA-approved antihistamine commonly marketed under the brand name Benadryl. It is found in a wide variety of brand-name OTC pain-relieving or fever-reducing medications , including Advil PM, Excedrin PM, Nytol, Tylenol PM, and ZzzQuil. Diphenhydramine is a first generation antihistamine and is traditionally used to treat ...

  2. Apr 7, 2022 · Diphenhydramine. Diphenhydramine (Benadryl) is a common ingredient in OTC sleep aids. It’s an antihistamine that’s used to treat allergy symptoms, like sneezing or itching. One of the main side effects of diphenhydramine is sleepiness. Because of this, it’s commonly used to help with sleep problems.

  3. Aug 11, 2023 · ZzzQuil Ultra Nighttime Sleep Aid. Now 14% Off. $19 at Amazon. Credit: ZzzQuil. Unlike NyQuil which also contains a pain reliever and cough suppressant, this product *just* contains 25 milligrams ...

  4. May 30, 2023 · Best natural sleep aid: ... find it difficult to fall and stay asleep: ... with a doctor about their sleep problems before using a new over-the-counter sleep aid. Last medically reviewed on May 30 ...

  5. Apr 16, 2024 · Find out more in my in-depth Natrol review. 2. Vitafusion SleepWell. 3mg melatonin combined with herbal ingredients. I’ve noticed a growing trend of over the counter sleep aids that combine melatonin and herbal ingredients, which are sometimes included to boost the sleep-promoting effect.

  6. Feb 23, 2022 · The best OTC sleep aid, according to doctors. Nature’s Way. Calm Aid - See at Nature's Way, Walgreens, and The Vitamin Shoppe. According to our experts, Nature's Way Calm Aid is one of the best ...

  7. Jul 13, 2021 · Over-the-counter sleep aids are best for use in the short term, to overcome a brief bout of sleeplessness or to cope with jet lag. They are generally not useful for long-term chronic insomnia.

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