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  1. 1 day ago · The causative agent, Borrelia burgdorferi, is transmitted to humans through the bite of an infected Ixodes tick. This pathogen uses many unique mechanisms to both shield itself from the host immune response and cause disease. Clinically, LD presents in successive phases, with each increasing in severity as the bacterial cells migrate to new ...

  2. 1 day ago · It is an infection caused by a bacteria called Borrelia burgdorferi. In the Mid-Atlantic region this bacteria is almost exclusively carried by the blacklegged deer ticks (ixodes scapularis). The infection is most commonly seen from late spring to early fall due to the life cycle of the tick. Signs and symptoms of Lyme disease include:

  3. 1 day ago · If a tick is infected with the pathogen Borrelia burgdorferi s. l. (sensu lato = in the broader sense), these bacteria can be transmitted to humans through a tick bite and cause illness. Various ...

  4. 5 days ago · A protein, P66 (CD47-like protein), was identified on the surface of Borrelia burgdorferi that is necessary and sufficient to bind the macrophage receptor SIRPα. This is the first research to identify the specific Borrelia protein that acts as a “don’t eat me” signal to the body’s immune system in people with Lyme disease. This helps ...

  5. 4 days ago · Researchers treated nerve tissue with live or inactivated Borrelia burgdorferi, followed by an application of FGFR inhibitors. Study results revealed a significant reduction in both inflammatory markers and of cell death.

  6. 1 day ago · Lyme Disease, caused by the bacterium Borrelia burgdorferi, is the most prevalent vector-borne disease. Recognizing Symptoms: Lyme Disease symptoms include fever, headaches, fatigue, and a distinct rash often characterized by a red center surrounded by a clear ring, resembling a bullseye. Preventive Measures:

  7. 1 day ago · This research discovered a groundbreaking new immune evasion strategy used by Borrelia burgdorferi, the bacterium causing Lyme disease. A specific Borrelia protein, P66, was identified as acting as a "don't eat me" signal to the immune system.

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