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  1. Dec 7, 2018 · ANSWER: Sepsis is a serious complication of an infection. It often triggers various symptoms, including high fever, elevated heart rate and fast breathing. If sepsis goes unchecked, it can progress to septic shock — a severe condition that occurs when the body’s blood pressure falls and organs shut down. Sepsis most often affects the ...

  2. Sepsis. Sepsis is a life-threatening condition that arises when the body’s response to infection causes injury to its own tissues and organs. It is frequently a final common pathway to death for many infectious diseases worldwide. It involves organ dysfunction caused by a dysregulated host response to infection and if not recognized early and ...

  3. Jun 12, 2023 · Sepsis syndromes span a clinical continuum with variable prognoses. Septic shock, the most severe complication of sepsis, carries high mortality. In response to an inciting agent, pro-inflammatory and anti-inflammatory arms of the immune system are activated in concert with the activation of monocytes, macrophages, and neutrophils that interact with the endothelium through pathogen recognition ...

  4. Jul 18, 2020 · Urinary tract infections (UTIs) are among the most common causes of sepsis presenting in hospitals. UTIs have a wide variety of presentations. Some are simple UTIs that can be managed with outpatient antibiotics and carry a reassuring clinical course with an almost universally good outcome. On the other end of the spectrum, florid urosepsis in a comorbid patient can be fatal. UTIs can also be ...

  5. Septic shock is the most dangerous kind of sepsis. You have very low blood pressure (shock), and many of your organs shut down. Septic shock can be fatal. Sepsis is caused by a bacterial infection that spreads to your bloodstream. People with a weakened immune system or certain diseases, such as diabetes or cirrhosis of the liver, are more ...

  6. In sepsis, blood pressure drops, resulting in shock. Major organs and body systems, including the kidneys, liver, lungs, and central nervous system may stop working properly because of poor blood flow. A change in mental status and very fast breathing may be the earliest signs of sepsis. In general, symptoms of sepsis can include:

  7. Apr 28, 2015 · The traditional definition of sepsis requires the presence of at least two ... the symptoms of SIRS while remaining at ... of severe sepsis and septic shock: 2012. Crit. Care Med. 41, 580–637 ...

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