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   How does a dengue virus interact with the host cellular machinery?

   • During dengue infection, the virus interacts with the host cellular machinery responsible for 5’ capping. DENV employs multiple strategies to hijack and manipulate this process. For instance, the virus sequesters essential host factors involved in capping, such as the cap-binding complex and associated enzymes.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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   How does a dengue virus internalize?

   • D Envelope glycoproteins attach to host receptors and form the dengue-host membrane complex, resulting in virus internalization to process its replication and propagation inside the host cell [ 13] Humans and mosquitoes are the primary hosts and vectors of DENV, respectively.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

   See all results for this question

   How does dengue spread?

   • The dengue virus is carried in the gut of female mosquitoes. When the insect bites an infected person and then feeds on someone else, it can spread the infection to that person. People cannot directly spread dengue to each other.

   What you need to know about the latest outbreak of dengue fever

   www.pbs.org/newshour/health/what-you-need-to-know-about-the-latest-outbreak-of-dengue-fever

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2. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com › articles › 10

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   Apr 22, 2024 · Dengue virus infection is known to induce endoplasmic reticulum (ER) stress, triggering signaling pathways associated with ER stress during viral infections. These pathways activate genes that support cell survival and anti-viral defenses.

3. www.who.int › news-room › fact-sheetsDengue and severe dengue - World Health Organization (WHO)

   www.who.int › news-room › fact-sheets

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   Apr 23, 2024 · The primary mode of transmission of the dengue virus between humans involves mosquito vectors. There is evidence however, of the possibility of maternal transmission (from a pregnant mother to her baby).

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5. journals.plos.org › plospathogens › articleThe inflammasome pathway is activated by dengue virus non ...

   journals.plos.org › plospathogens › article

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   Apr 25, 2024 · Dengue, caused by dengue virus (DENV), is the most prevalent mosquito-transmitted disease in humans and a significant public health issue worldwide. DENV nonstructural protein 1 (NS1) has been shown to contribute to dengue pathogenesis through the induction of endothelial barrier dysfunction, resulting in hyperpermeability and vascular leak–a ...

6. link.springer.com › article › 10Role of auto-antibodies in the mechanisms of dengue ...

   link.springer.com › article › 10

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   Apr 15, 2024 · A complex interaction among virulence factors, host-genes and host immune system is considered to be responsible for dengue virus (DENV) infection and disease progression. Generation of auto-antibodies during DENV infection is a major phenomenon that plays a role in the pathophysiology of dengue hemorrhagic fever and dengue shock syndrome.

7. www.pbs.org › newshour › healthWhat you need to know about the latest outbreak of dengue ...

   www.pbs.org › newshour › health

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   Apr 12, 2024 · The dengue virus is carried in the gut of female mosquitoes. When the insect bites an infected person and then feeds on someone else, it can spread the infection to that person. People cannot ...

   • Author: Laura Santhanam

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9. www.science.org › doi › 10Antigenic distance between primary and secondary dengue ...

   www.science.org › doi › 10

   Apr 24, 2024 · In the case of dengue virus (DENV), an arbovirus that infects more than 100 million people each year, the situation is even more complex (4, 5). Individuals with high DENV antibody titers are protected from infection and developing severe disease (6–8).

10. www.nature.com › articles › s41598/024/57930-1A 2D-proteomic analysis identifies proteins differentially ...

    www.nature.com › articles › s41598/024/57930-1

    Apr 9, 2024 · Published: 09 April 2024. A 2D-proteomic analysis identifies proteins differentially regulated by two different dengue virus serotypes. Chanida Chumchanchira, Suwipa Ramphan, Atchara Paemanee,...