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1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.

2. www.cell.com › trends › molecular-medicineMolecular mechanisms in the pathogenesis of dengue infections

   www.cell.com › trends › molecular-medicine

   4 days ago · Dengue is the most rapidly emerging climate-sensitive infection, and morbidity/mortality and disease incidence are rising markedly, leading to healthcare systems being overwhelmed. There are currently no specific treatments for dengue or prognostic markers to identify those who will progress to severe disease. Owing to an increase in the burden of illness and a change in epidemiology, many ...

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4. www.ncbi.nlm.nih.gov › pmc › articlesDengue virus: A global human threat: Review of literature

   www.ncbi.nlm.nih.gov › pmc › articles

   A cute-onset high fever, muscle and joint pain, myalgia, cutaneous rash, hemorrhagic episodes, and circulatory shock are the commonly seen symptoms. Oral manifestations are rare in dengue infection; however, some cases may have oral features as the only presenting manifestation.

   • Author: Shamimul Hasan, Sami Faisal Jamdar, Munther Alalowi, Sadun Mohammad Al Ageel Al Beaiji
   • DOI: 10.4103/2231-0762.175416

   • Publish Year: 2016
   • Published: Jan-Feb 2016

5. www.ncbi.nlm.nih.gov › pmc › articlesCollateral Damage during Dengue Virus Infection: Making Sense ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jul 7, 2017 · These findings highlight the relevance of the DNA-sensing mechanism in the detection and control of infections by RNA viruses. In this review, we discuss how DENV modulates the innate immune DNA-sensing pathway, activated in the context of cellular damage during infection.

   • Author: Sebastian Aguirre, Ana Fernandez-Sesma
   • DOI: 10.1128/JVI.01081-16

   • Publish Year: 2017
   • Publication: J Virol. 2017 Jul 15; 91(14): e01081-16.

6. www.nature.com › articles › nrdp201655Dengue infection | Nature Reviews Disease Primers

   www.nature.com › articles › nrdp201655

   Aug 18, 2016 · Four main factors control dengue virus (DENV) disease response along a response continuum: immune status, virus strain, genetic status and age. Individuals at risk of a secondary infection are...

   • Author: Maria G. Guzman

7. People also ask

   Are there any controversies about the pathogenesis of dengue fever?

   • In this paper, six controversies in relation to the pathogenesis of dengue fever are analysed and, where possible, resolved. Rosen, L. The Emperor's New Clothes revisited, or reflections on the pathogenesis of dengue hemorrhagic fever.

   Dengue infection | Nature Reviews Disease Primers

   www.nature.com/articles/nrdp201655

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   What causes severe manifestations of dengue virus disease?

   • The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

   See all results for this question

   How does severe dengue affect the respiratory system?

   • The capillary leakage involved in severe dengue can have consequences for the respiratory system. These can include pleural effusion and respiratory distress associated with pulmonary oedema, which can be worsened by over-hydration during fluid therapy 267.

   Dengue infection | Nature Reviews Disease Primers

   www.nature.com/articles/nrdp201655

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8. link.springer.com › content › pdfProgress towards understanding the pathogenesis of dengue ...

   link.springer.com › content › pdf

   DENV infection results in a broad spectrum of clinical symptoms, ranging from mild fever to dengue hemorrhagic fever (DHF), the latter of which can progress to dengue shock syndrome (DSS) and death. Researchers have made unremitting efforts over the last half-century to understand DHF pathogenesis.

9. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

   www.sciencedirect.com › science › article

   May 1, 2024 · Possible direct effects of dengue virus (DENV) in causing disease pathogenesis. DENV is detected by retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA-5) that induce type I and III interferon (IFN) production.