Search results
Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.
- Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
- 10.1007/s00284-020-02284-w
- 2021
- Curr Microbiol. 2021; 78(1): 17-32.
May 1, 2024 · Many mechanisms contribute to liver dysfunction, including prolonged shock that causes hypoxic damage, direct liver cell death due to infection with the virus, and immune-mediated effects. Bleeding following dengue virus infection occurs due to multiple mechanisms including platelet activation by NS1, serotonin, and PAF, accompanied by a wide ...
Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...
- 10.1155/2021/4224816
- 2021
- Biomed Res Int. 2021; 2021: 4224816.
Dengue is the most rapidly emerging climate-sensitive infection, and morbidity/mortality and disease incidence are rising markedly, leading to healthcare systems being overwhelmed. There are currently no specific treatments for dengue or prognostic markers to identify those who will progress to severe disease. Owing to an increase in the burden of illness and a change in epidemiology, many ...
Apr 12, 2012 · VOL. 366 NO. 15. Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a public health challenge with an ...
People also ask
Are there any controversies about the pathogenesis of dengue fever?
What causes severe manifestations of dengue virus disease?
What is the pathogenesis of dengue?
Jan 24, 2019 · Dengue is a viral illness that is spread primarily by Aedes mosquitoes and infects ~390 million people each year worldwide 1.It is caused by dengue virus (DENV), which belongs to the family of ...
Aug 18, 2016 · Four main factors control dengue virus (DENV) disease response along a response continuum: immune status, virus strain, genetic status and age. Individuals at risk of a secondary infection...
