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1. • • The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.
     www.ncbi.nlm.nih.gov › pmc › articles

     Current Understanding of the Pathogenesis of Dengue Virus ...

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   What is the pathogenesis of dengue?

   • The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What type of virus causes dengue?

   • Dengue is caused by one of four single-stranded, positive-sense RNA viruses (dengue virus type 1 through dengue virus type 4), also referred to as serotypes) of the genus flavivirus (family Flaviviridae).

   Dengue | New England Journal of Medicine

   www.nejm.org/doi/full/10.1056/NEJMra1110265

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   What is a dengue virus (DENV)?

   • Dengue viruses (DENVs) cause the most common arthropod-borne viral disease in man with 50–100 million infections per year. Because of the lack of a vaccine and antiviral drugs, the sole measure of control is limiting the Aedes mosquito vectors. DENV infection can be asymptomatic or a self-limited, acute febrile disease ranging in severity.

   Dengue viruses – an overview - PMC - National Center for

   www.ncbi.nlm.nih.gov/pmc/articles/PMC3759171/

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3. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · Dengue is a mosquito-borne Flavivirus infection, primarily transmitted by Aedes aegypti followed by Aedes albopictus mosquito and other species of genus Aedes [ 1, 4]. There are four serotypes of dengue virus which are antigenically distinct namely DENV-1, DENV-2, DENV-3, and DENV-4 [ 5 ].

   • Fig. 1

     The pathogenesis of dengue virus infection is attributed to...

   • Dengue Virus

     Abstract. Dengue virus (DENV) belongs to the family...

   • An Overview

     DENV infection induces intracellular membrane alterations in...

4. en.wikipedia.org › wiki › Dengue_virusDengue virus - Wikipedia

   en.wikipedia.org › wiki › Dengue_virus

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   A recent systematic review and meta-analysis showed that allergic symptoms are one of the core symptoms that are highly associated with dengue severity. Mechanism of infection. Dengue virus' (DENV) E envelope protein binds to a cellular receptor. The exact nature of the cellular receptor has not been fully elucidated.

   • Class: Flasuviricetes
   • Genus: Flavivirus

   • Family: Flaviviridae
   • Phylum: Kitrinoviricota

5. www.nature.com › scitable › topicpageDengue Viruses | Learn Science at Scitable - Nature

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   Introduction. Viruses are tiny agents that can infect a variety of living organisms, including bacteria, plants, and animals. Like other viruses, the dengue virus is a...

6. www.who.int › news-room › fact-sheetsDengue and severe dengue - World Health Organization (WHO)

   www.who.int › news-room › fact-sheets

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   Mar 17, 2023 · The primary mode of transmission of the dengue virus between humans involves mosquito vectors. There is evidence however, of the possibility of maternal transmission (from a pregnant mother to her baby).

7. www.nejm.org › doi › fullDengue | New England Journal of Medicine

   www.nejm.org › doi › full

   Apr 12, 2012 · Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a public health challenge with...