Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Five serotypes of the virus have been found, all of which can cause the full spectrum of disease.
Dengue fever is one of the major health problems in India. Interaction with specific receptor(s) at the cell surface is one of the first events in the pathogenesis of Dengue virus. However, relatively little is known about these receptors. Cellular receptors in human monocytes and mouse neural cells are main target for the viral infection.
- Seema, S. K. Jain
Dengue fever, an infectious tropical disease caused by a mosquito-borne virus, afflicts millions of people each year, causing fever, headache, muscle and joint pains and a characteristic skin rash.
Mechanism of dengue virus entry into cells uncovered by research Date: February 17, 2014 Source: Biophysical Society Summary: Despite its heavy toll, the prevention and clinical treatment of ...
Dengue is a mosquito-borne viral infection. The virus responsible for causing dengue, is called dengue virus (DENV). There are four types of DENV serotypes (DENV1, DENV2, DENV3 and DENV4), meaning that it is possible to be infected four times. The global incidence of dengue has grown dramatically in recent decades.
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The dengue virus is considered to be a globally important human pathogen prevalent in tropical and subtropical regions of the world. According to a recent estimate, the disease burden due to DENV infections is ~390 million infections per year globally in ~100 countries including the southern US, Puerto Rico and Hawaii, resulting in nearly ...
Mechanism of Dengue Virus Entry into Cells by Global Biodefense February 26, 2014, 2:48 pm Dengue fever, an infectious tropical disease caused by a mosquito-borne virus, afflicts millions of people each year, causing fever, headache, muscle and joint pains and a characteristic skin rash.
Dengue fever virus (DENV) is an RNA virus of the family Flaviviridae; genus Flavivirus.Other members of the same genus include yellow fever virus, West Nile virus, Zika virus, St. Louis encephalitis virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kyasanur forest disease virus, and Omsk hemorrhagic fever virus.
e-mediated process. Recent findings Significant findings in the past year include a greater understanding of dengue virus interactions with target cells such as dendritic cells, hepatocytes and endothelial cells. Infection of these cells results in the production of immune mediators that then shape the adaptive humoral and cellular immune response. The circulation of high levels of secreted ...
The virus that causes dengue is transmitted by mosquitoes. Dengue fever usually starts with a fever, joint pain, rash and nausea. Without treatment, the virus can cause damage to blood and lymph vessels and lead to dengue hemorrhagic fever, which is marked by difficulty breathing, bruising and bleeding from the nose, gums or under the skin.