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Aug 6, 2011 · Dengue virus is an arthropod-borne virus transmitted by Aedes mosquitoes. Dengue virus causes fever and hemorrhagic disorders in humans and non-human primates. Direct interaction of the virus introduced by a mosquito bite with host receptor molecule (s) is crucial for virus propagation and the pathological progression of dengue diseases.
Mar 14, 2024 · Environmental suitability for dengue transmission is expanding due to climate change, urbanisation and international travel 3. It is predicted that 2.25 (1.27–2.80) billion more people will be ...
Nov 21, 2022 · Dengue virus (DENV) infection is one of the major public health concerns around the globe, especially in the tropical regions of the world that contribute to 75% percent of dengue cases. While the majority of DENV infections are mild or asymptomatic, approximately 5% of the cases develop a severe form of the disease that is mainly attributed to ...
Nov 25, 2015 · Dengue virus (DENV) infections of humans were long thought to be self-limited and of low mortality. Beginning in the 1950s, at the time when four different DENVs were discovered, a lethal variant of dengue emerged. Dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) initially observed in Southeast Asia now has spread throughout the world.
The four closely related dengue viruses — DEN-1, DEN-2, DEN-3, and DEN-4 — are found in the same regions of the world. The dengue virus has a roughly spherical structure.
Feb 23, 2022 · In recent decades, the incidence of AKI associated with dengue virus infection has increased significantly 10 . Severe dengue affects about 6.0 to 6.7% of patients diagnosed with dengue 17 18 . Among hospitalized patients with severe dengue 3.3% to 4.8% develop AKI, of which 14.1% require dialysis 17 19 24 .
Mar 4, 2019 · In this study, we obtained five DENV1 isolates (DENV1 A to E) from the outbreak of dengue fever in 2014 of Guangzhou, China, and analyzed their replication efficiency and virulence in vitro and in vivo. The results suggested that among the five DENV1 strains, DENV1 B has the highest replication efficiency in both human and mosquito cells in ...
