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  1. www.ncbi.nlm.nih.gov › pmc › articlesDengue Virus

    Sep 20, 2019 · Genomic Structure of Dengue Virus. The DENV genome consists of a single, positive-strand RNA of ~11 kb. A type I cap is present at the 5′ end, followed by the conserved dinucleotide 5′-AG-3′ (Cleaves and Dubin, 1979). The 3′ end of the genome lacks a polyadenylate tail and terminates in a conserved 5′-CU-OH 3′ (Wengler and Wengler, 1981

  2. The dengue virus is a single-strand RNA virus with a spherical shape and four serotypes. It has a nucleocapsid, a membrane, and two envelope proteins that form a protective outer layer. The virus replicates inside the cell and infects the host by endocytosis.

  3. Learn about the spherical shape and composition of the dengue virus, a microscopic structure that can only replicate inside a host organism. See how the virus hijacks the host cell's machinery and forms a protective outer layer with E and M proteins.

  4. en.wikipedia.org › wiki › Dengue_virusDengue virus - Wikipedia

    Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, all of which can cause the full spectrum of disease.

  5. Feb 17, 2022 · Dengue virus NS4B is a membrane protein consisting of 248 residues with a molecular weight of approximately 27 kDa ( Figure 5 A). It is an important component of the viral replication complex on the ER membrane and colocalized with NS3 and viral double-stranded RNA [ 123, 124, 125, 126 ].

    • Qingxin Li, Congbao Kang
    • Membranes (Basel). 2022 Feb; 12(2): 231.
    • 10.3390/membranes12020231
    • 2022/02
  6. Aug 30, 2013 · Dengue is an acute febrile disease caused by the mosquito-borne dengue viruses (DENVs), consisting of four serotypes (DENV 1 to 4), that are members of the family, genus flavivirus ( 1 ). All four DENV serotypes have emerged from sylvatic strains in the forests of South-East Asia ( 2 ).

  7. Oct 1, 2023 · Abstract. Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS). Due to a lack of antiviral drugs and effective vaccines, several therapeutic and control strategies have been proposed.

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