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  1. 5 days ago · April 21, 2024. in Neuroimaging. Photo credit: NIDA. Individuals with stronger depressive symptoms and those who experienced stressful life events tend to show alterations in volume of the nucleus acumbens, according to new research. Additional changes in the volume and functional connectivity of specific brain regions were also observed.

  2. 2 days ago · We find that MDMA robustly enhances both the social transfer of pain and analgesia and that the drug’s action in the nucleus accumbens (NAc) core alone is sufficient to produce these effects. Moreover, optogenetic stimulation of serotonin (5-HT) inputs in the NAc core similarly enhances empathy, suggesting a key role for MDMA-mediated 5-HT ...

  3. 3 days ago · The potential therapeutic role of DBS in SE-AN was also assessed in a case report by Arroteia et al., where they described impressive weight gain in a 42-year-old woman suffering from chronic and treatment-resistant AN (bulimic subtype) after 12 months of bilateral Nucleus Accumbens (NAcc) DBS . DBS of the NAcc is a treatment option that should ...

  4. 2 days ago · For instance, OT release in the amygdala is known to have anxiolytic effects 21 but also to be important for social recognition. 52, 57 In the nucleus accumbens, OT is involved in social reward 58 and regulates pair bonding in voles. 4 It would thus be very interesting to manipulate OT in these areas in marmosets, as these highly social monkeys ...

  5. 1 day ago · We were primarily interested in connections between subcortical and frontal regions, as well as connections between subcortical regions, that have been related to cognitive, neuropsychiatric, and motor processes. 46-48 Subcortical ROIs therefore included the hippocampus (Hip), amygdala (Amy), nucleus accumbens (NAc), caudate nucleus (Cau), and ...

  6. 1 day ago · Zhou C, Xue C, Chen J, Amdanee N, Tang X, Zhang H, Zhang F, Zhang X, Zhang C (2021) Altered functional connectivity of the nucleus accumbens network between deficit and non-deficit schizophrenia. Front Psychiatry 12:704631. Article PubMed PubMed Central Google Scholar

  7. 2 days ago · The environment influences brain and mental health, both detrimentally and beneficially. Existing research has emphasised the individual psychosocial ‘microenvironment’. Less attention has ...

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