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  1. 22 hours ago · Researchers genotyped murine samples to quantify genetic expression in the ECM of lean and obese mice's mediobasal hypothalamus. To explore its therapeutic potential, fluorosamine, a drug that prevents chondroitin sulfate synthesis, was administered intranasally and injected into the cerebrospinal fluid of mice for ten days.

  2. Sep 20, 2024 · This may be attributed to the anorectic properties of proinflammatory cytokines where Interleukin (IL)-1β stimulates intestinal cholecystokinin release, and tumor necrosis factor (TNF)-α modulates glucose-sensitive neurons in the hypothalamus, which impact eating behavior (Saracino et al. 2023).

  3. 22 hours ago · Several extrathyroidal locations of the receptor have been found including: the pituitary, the hypothalamus, and other areas of the central nervous system; the periorbital tissue; the skin; the kidney; the adrenal; the liver; the immune system cells; blood cells and vascular tissues; the adipose tissue; the cardiac and skeletal muscles, and the ...

  4. 22 hours ago · Non-steroidal anti-inflammatory drugs[1][3] (NSAID) [1] are members of a therapeutic drug class which reduces pain, [4] decreases inflammation, decreases fever, [1] and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of gastrointestinal ulcers and bleeds, heart ...

  5. 7 hours ago · Girls exposed to certain endocrine-disrupting chemicals (EDCs) may be more likely to start puberty early, according to new research published in Endocrinology, the flagship basic science journal of the Endocrine Society. EDCs mimic, block or interfere with hormones in the body's endocrine system. There has been an alarming trend toward early ...

  6. www.franktalk.org › phpBB3 › viewtopicFrankTalk

    22 hours ago · Humor and Fun ... "As Donkeykong says, I can often inject painlessly with 31g because it's thin enough to go between nerves. I start by moving around prodding and when I find ...

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  8. 22 hours ago · hypothalamus, pituitary gland, gonads, and liver. Traditionally linked to photoperiod changes, recent studies suggest metabolic triggers can independently stimulate maturation. This study investigated how different growth trajectories influence body weight (BW) and body composition

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