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  1. Number of deaths for leading causes of death. Heart disease: 695,547. Cancer: 605,213. COVID-19: 416,893. Accidents (unintentional injuries): 224,935. Stroke (cerebrovascular diseases): 162,890. Chronic lower respiratory diseases: 142,342. Alzheimer’s disease: 119,399. Diabetes: 103,294.

  2. The top global causes of death, in order of total number of lives lost, are associated with three broad topics: cardiovascular (ischaemic heart disease, stroke), respiratory (chronic obstructive pulmonary disease, lower respiratory infections) and neonatal conditions – which include birth asphyxia and birth trauma, neonatal sepsis and infections...

  3. Heart disease and cancer remained the top 2 leading causes in 2022. The infant mortality rate was 560.4 infant deaths per 100,000 live births in 2022, an increase of 3.1% from the rate in 2021 (543.6). This report presents final 2022 U.S. mortality data on deaths and death rates by demographic and medical characteristics.

  4. On this page, you will find global data and research on leading causes of death and how they can be prevented. This includes the number of people dying from each cause, their death rates, how they differ between age groups, and their trends over time.

  5. Heart disease, cancer, and COVID-19 remained the top 3 leading causes. The infant mortality rate was 543.6 infant deaths per 100,000 live births in 2021. The change in infant mortality from 2020 was not statistically significant.

  6. Oct 4, 2023 · Leading causes of death. IHME - GBD (2019) See all data and research on: Causes of Death. Explore the Data. Sources & Processing. Reuse This Work. What you should know about this indicator. For each country-year the disease or injury that caused the most deaths according to the IHME - Global Burden of Disease Study (2019).

  7. Summary findings. Noncommunicable diseases have become more prominent with Alzheimer’s disease and diabetes entering whereas communicable diseases are on the decline with both HIV and tuberculosis dropping out of the top 10. Ischaemic heart disease was the top cause of death in both 2000 and 2019.

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