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The nucleus accumbens (NAc or NAcc; also known as the accumbens nucleus, or formerly as the nucleus accumbens septi, Latin for 'nucleus adjacent to the septum') is a region in the basal forebrain rostral to the preoptic area of the hypothalamus. The nucleus accumbens and the olfactory tubercle collectively form the ventral striatum.
- NAc or NAcc
- Nucleus accumbens shell, Nucleus accumbens core
- nucleus accumbens septi
Oct 30, 2023 · The nucleus accumbens is involved in various cognitive, emotional, and psychomotor functions. It serves as an important area for motivation, reward and pleasure, addiction, impulsivity and risk taking behaviours. It is also involved in the control of survival and reproductive behaviours.
- Medical Content
- 22 min
Sep 21, 2023 · The nucleus accumbens is a region in the brain's basal forebrain that plays a critical role in the reward circuit. It is involved in pleasure, reinforcement learning, and the processing of motivation and reward. Dysregulation of this area is often implicated in addiction, depression, and other psychiatric disorders.
When rewarding stimuli are experienced, the dopaminergic mesolimbic system is activated which causes the release of dopamine to the targeted nuclei ( Small et al. 2003; Cameron et al. 2014 ). The ventral striatum, including the nucleus accumbens (NAcc), is a major substrate involved in reward ( Marche et al. 2017 ).
- 10.1007/978-3-030-81147-1_4
- 2021
Oct 18, 2019 · The nucleus accumbens (NAc) is a subcortical brain structure known primarily for its roles in pleasure, reward, and addiction. Despite less focus on the NAc in pain research, it also plays a large role in the mediation of pain and is effective as a source of analgesia.
- Haley N Harris, Yuan B Peng
- 10.4103/1673-5374.266909
- 2020
- Neural Regen Res. 2020 Apr; 15(4): 597-605.
The nucleus accumbens (NAc) is a key node of the brain’s circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors.
A target of increasing interest is the nucleus accumbens (NAc), which has long been studied as a key brain region mediating a variety of behaviors, including reward and satisfaction.
