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Apr 2, 2013 · Drug Testing and Analysis is a specialist journal covering sports doping, recreational drugs, pharmaceuticals, toxico-pathology, forensics, and the environment.
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An arylcyclohexylamine is composed of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned geminal to the amine. In the simplest cases, the aryl moiety is typically a phenyl ring, sometimes with additional substitution. The amine is usually not primary; secondary amines such as methylamine or ethylamine, or ...
CompoundAryl SubstituentN GroupCyclohexyl Ring2-HO-PCPPhenylPiperidine2-Hydroxy2-Me-PCPPhenylPiperidine2-Methyl2-MeO-PCPPhenylPiperidine2-Methoxy2-Keto-PCPPhenylPiperidine2-KetoPeople also ask
Which arylcyclohexylamine was first synthesised?
When was phenyl cyclohexylamine used?
What is arylcyclohexylamine?
What was the first arylcyclohexamine?
Alkylation is an efficient method for the synthesis of 3 o and 4 o amines. However, when 1 o and 2 o amines are alkylated a mixture of products is typically produced. When ammonia is reacted with an alkylhalide an monoalkylammonium salt is formed. RX + NH 3 → RNH 3+ + X -.
Jan 1, 2016 · The first arylcyclohexamine to be described was 1-(1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP . Other analogues reported in the early 1950s included N-ethyl-1-phenylcyclohexylamine (PCE) and 1-(1-phenylcyclohexyl)morpholine (PCMo). While many were not explored further by their initial investigators, chemists ...
May 1, 1990 · Several analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, exhibited a greater separation of potencies in the motor toxicity and MES seizure tests than did the parent compound PCA. Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a ...
Feb 6, 2010 · IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2 Copy IUPAC Standard InChIKey: TXTHKGMZDDTZFD-UHFFFAOYSA-N ...
Sep 1, 2011 · Synthesis of 1-phenylcyclopentylamine (8a) and 1-phenylcyclohexylamine (8b) 5.2.1. 1-Phenylcyclopentanol (6a) Magnesium turnings (217 mg, 8.93 mmol) in dry THF (5 mL) was placed in ice cold water and iodobenzene (0.73 mL, 6.55 mmol) in dry THF (2 mL) was added dropwise over 10 min.
