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1. • • The PCOH starting material can be purchased or prepared by reaction of phenyllithium or phenyl grignard with cyclohexanone. This alcohol is then be transformed into the amine by reaction with sodium azide (~90% yield) followed by reduction.
     chemistry.mdma.ch › hiveboard › rhodium

     Use of PCA (1-phenylcyclohexylamine) as a precursor

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   What was the first arylcyclohexamine?

   • The first arylcyclohexamine to be described was 1- (1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP [ 1 ]. Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1- (1-phenylcyclohexyl)morpholine (PCMo).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Does chronic use of arylcyclohexamines affect working memory?

   • The subsequent reduction in dopaminergic activity seen with chronic use of arylcyclohexamines also plays a role in decreased working memory function of the prefrontal cortex [ 226 ].

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Are there any arylcyclohexamine analogues?

   • The only case series of other arylcyclohexamine analogues comes from the Swedish STRIDA project, which reported 59 cases of acute 3- and 4-MeO-PCP toxicity [ 101 ]; 86.4 % were male and the median age was 26 years.

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   What are the main effects of arylcyclohexamines?

   • Chemical structures of the primary arylcyclohexamines: phencyclidine , ketamine , and methoxetamine The main effects of this class of agents are nystagmus, hypertension, and tachycardia in a behaviorally disturbed, and possibly violent, patient.

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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3. pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine1-Phenylcyclohexylamine | C12H17N | CID 31862 - PubChem

   pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine

   Oct 14, 2021 · 1-Phenylcyclohexylamine | C12H17N | CID 31862 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

4. analyticalsciencejournals.onlinelibrary.wiley.comPreparation and analytical characterization of 1‐(1 ...

   analyticalsciencejournals.onlinelibrary.wiley.com

   Apr 2, 2013 · The present study describes the synthesis of three substituted 1-(1-phenylcyclohexyl)piperidines, (3-MeO-, 4-MeO- and 3-Me-PCP) and three substituted 1-(1-phenylcyclohexyl)pyrrolidine analogues (3-MeO-, 4-MeO- and 3-Me-PCPy).

   • Author: Jason Wallach, Giorgia De Paoli, Adeboye Adejare, Simon D. Brandt

   • Publish Year: 2014

5. www.erowid.org › archive › rhodiumThe Synthesis of Phencyclidine and Other 1 ... - Erowid

   www.erowid.org › archive › rhodium

   The compounds were prepared by several procedures. 1-( I-Pheiiylcyclohesyl)piperidine, the first compouiid of this type synthesized, was prepared from I-piperidinocyclohexanecarbonitrile by replacement of the cyano group by phenyl using phenylmagnesirim bromide.

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6. link.springer.com › referenceworkentry › 10Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com › referenceworkentry › 10

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   Jan 1, 2016 · Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1).

7. chemistry.mdma.ch › hiveboard › rhodiumUse of PCA (1-phenylcyclohexylamine) as a precursor

   chemistry.mdma.ch › hiveboard › rhodium

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   Synthesis of PCP from PCA via 1-phenylcyclohexanol (PCOH) The PCOH starting material can be purchased or prepared by reaction of phenyllithium or phenyl grignard with cyclohexanone. This alcohol is then be transformed into the amine by reaction with sodium azide (~90% yield) followed by reduction.

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9. www.semanticscholar.org › paper › Synthesis-andSynthesis and anticonvulsant activity of 1 ... - Semantic Scholar

   www.semanticscholar.org › paper › Synthesis-and

   May 1, 1990 · Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a motor-toxicity assay.

10. webbook.nist.gov › cgi › cbookN-Phenylcyclohexylamine - NIST Chemistry WebBook

    webbook.nist.gov › cgi › cbook

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    N-Phenylcyclohexylamine. Formula: C 12 H 17 N. Molecular weight: 175.2701. IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11 (8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2. Copy Sheet of paper on top of another sheet.