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  1. Mar 21, 2019 · Sepsis is a systemic response to infection, manifested by two or more of the SIRS criteria as a result of infection. Severe sepsis: Sepsis associated with organ dysfunction, hypoperfusion, or hypotension; hypoperfusion and perfusion abnormalities may include, but not limited to, lactic acidosis, oliguria, or an acute alteration in mental status

  2. May 23, 2016 · In its most severe form, sepsis causes multiple organ dysfunction that can produce a state of chronic critical illness characterized by severe immune dysfunction and catabolism. Much has been learnt about the pathogenesis of sepsis at the molecular, cell, and intact organ level.

  3. May 21, 2023 · Review the pathophysiology of bacterial sepsis. Describe the typical lab findings in bacterial sepsis. Summarize the components of the acute sepsis bundle and the components of the sepsis management bundle used in the evaluation and treatment of patients with sepsis.

  4. Jan 9, 2003 · The Pathophysiology and Treatment of Sepsis. Authors: Richard S. Hotchkiss, M.D., and Irene E. Karl, Ph.D. Author Info & Affiliations. Published January 9, 2003. N Engl J Med 2003;348: 138 -...

  5. Aug 24, 2023 · Print. On this Page. Anyone can get an infection, and almost any infection, including COVID-19, can lead to sepsis. In a typical year: At least 1.7 million adults in America develop sepsis. At least 350,000 adults who develop sepsis die during their hospitalization or are discharged to hospice.

  6. Jan 19, 2023 · Overview. What is sepsis? Sepsis is a life-threatening medical emergency caused by your bodys overwhelming response to an infection. Without urgent treatment, it can lead to tissue damage, organ failure and death. Sepsis definition. Sepsis is your body’s extreme reaction to an infection.

  7. Jul 19, 2023 · Sepsis is a serious condition that happens when the body’s immune system has an extreme response to an infection. The body’s reaction causes damage to its own tissues and organs. Sepsis can affect anyone, but people who are older, very young, pregnant or have other health problems are at higher risk.

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