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  1. Stiff Person Syndrome is an autoimmune and neurological disorder that causes rigidity and spasms in the trunk and limbs. Learn about symptoms and treatment.

  2. Apr 25, 2024 · Stiff person syndrome (SPS), also known as Moersch-Woltman syndrome, and formerly known as “stiff man syndrome,” is a rare, immune-mediated neurological movement disorder characterized by rigidity, stiffness, and sudden painful spasms, particularly in the axial and proximal appendicular muscles (e.g., spinal and abdominal, as well as muscles of ...

  3. Dec 8, 2022 · December 8, 2022. Stiff-person syndrome is an autoimmune disorder of the nervous system, often resulting in progressive, severe muscle stiffness and spasms of the lower extremities and back. It also can affect other body regions.

  4. Stiff person syndrome is so rare that in the U.S., fewer than 5,000 living people have been diagnosed with it. ... helping them to live as normal of a life as possible. ...

  5. Dec 8, 2022 · And like many chronic conditions, the associated complications can lead to shortened life expectancy. Who is at risk of stiff person syndrome?

  6. Nov 28, 2023 · What is stiff-person syndrome? Stiff-person syndrome (SPS) is a rare, progressive neurological disorder. Symptoms may include: Stiff muscles in the trunk (torso), arms, and legs; Greater sensitivity to noise, touch, and emotional distress, which can set off muscle spasms Over time people with SPS may develop hunched over postures.

  7. Key Points. Stiff-person syndrome is a CNS disorder that causes progressive muscle stiffness and spasms. (See also Overview of Peripheral Nervous System Disorders.) Stiff-person syndrome (formerly called stiff-man syndrome) affects the central nervous system (CNS) but has neuromuscular manifestations.

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