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Aug 21, 2017 · Dopamine innervation to the cerebral hemispheres originates in the substantia nigra (SN) and ventral tegmental area (VTA) of the midbrain. In monkeys, SN/VTA dopamine neurons display variations in both anatomy and function.
May 15, 2022 · The substantia nigra is a brain structure that is part of your basal ganglia. While it’s very small, this structure is essential in how your brain controls your body’s movements. It also plays a part in the chemical signaling in your brain, which affects learning, mood, judgment, decision-making and other processes.
Oct 30, 2023 · The substantia nigra, also known as the black nucleus, is a large gray matter structure of the mesencephalon or midbrain (middle brain). It gets its name from its dark appearance on the cross-sections of the brain ( Latin for 'Black substance'). The dark coloration comes from the high number of neurons that contain the substance neuromelanin .
Oct 24, 2022 · The substantia nigra (SN) is a midbrain dopaminergic nucleus which has a critical role in modulating motor movement and reward functions as part of the basal ganglia circuitry. Projections from the SN to the putamen, called the nigrostriatal pathway, are critically involved in the motor deficits obs …
Aug 21, 2020 · Nature Communications - The substantia nigra is important in neurological disease, particularly movement disorders. Here the authors provide a single cell transcriptomic atlas for the human ...
Jan 25, 2024 · While anatomical studies have suggested the presence of cerebellar projections to the substantia nigra pars compacta (SNc), the nature and function of these connections (Cb–SNc) is unknown....
Oct 4, 2022 · The substantia nigra (SN) is a small yet essential brain structure that plays a critical role in controlling your body's movements. By producing dopamine, the substantia nigra controls motor...
