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The ventral tegmental area, or VTA, is in the midbrain, situated adjacent to the substantia nigra. Although it contains several different types of neurons, it is primarily characterized by its dopaminergic neurons, which project from the VTA throughout the brain.
Ventral tegmental area (VTA) contains cell bodies of dopaminergic neurons projecting to the nucleus accumbens, amygdala, hippocampus, and prefrontal cortex. Defined as the mesocorticolimbic dopamine system ( Albanese and Minciacchi, 1983 ), these neurons are critically implicated in brain mechanisms of reward, reinforcement, and emotional ...
Mar 29, 2019 · The ventral tegmental area (VTA) is a heterogeneous midbrain structure, containing neurons and astrocytes, that coordinates behaviors by integrating activity from numerous afferents.
Oct 14, 2012 · Nature - Dopamine neurons in the ventral tegmental area (VTA) are perhaps best known for their reward-related activity, but they can also signal aversion. Here, the authors show that...
Nov 10, 2015 · Abstract. The ventral tegmental area (VTA) is involved in adaptive reward and motivation processing and is composed of dopamine (DA) and GABA neurons. Defining the elements regulating activity and synaptic plasticity of these cells is critical to understanding mechanisms of reward and addiction.
May 1, 2019 · PMID: 30710678. DOI: 10.1016/j.neuroimage.2019.01.062. Abstract. The ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) are assumed to play a key role in dopamine-related functions such as reward-related behaviour, motivation, addiction and motor functioning.
Both aversive and rewarding stimuli rapidly and potently excite dopamine neurons in the ventral tegmental area (VTA). Furthermore, these seemingly opposite experiences interact with each other at both a neural and behavioral level.
