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Jan 5, 2017 · Ventral tegmental area (VTA) dopamine neurons (which we here define as those neurons that express the dopamine-producing enzyme tyrosine hydroxylase (TH) and release dopamine ( Box 1) are...
Ventral tegmental area (VTA) contains cell bodies of dopaminergic neurons projecting to the nucleus accumbens, amygdala, hippocampus, and prefrontal cortex. Defined as the mesocorticolimbic dopamine system ( Albanese and Minciacchi, 1983 ), these neurons are critically implicated in brain mechanisms of reward, reinforcement, and emotional ...
Mar 29, 2019 · The ventral tegmental area (VTA) is a heterogeneous midbrain structure, containing neurons and astrocytes, that coordinates behaviors by integrating activity from numerous afferents.
Jun 17, 2020 · The ventral tegmental area (VTA), an important source of dopamine, regulates goal- and reward-directed and social behaviors, wakefulness, and sleep. Hyperactivation of dopamine neurons...
Both aversive and rewarding stimuli rapidly and potently excite dopamine neurons in the ventral tegmental area (VTA). Furthermore, these seemingly opposite experiences interact with each other at both a neural and behavioral level.
Nov 10, 2015 · Abstract. The ventral tegmental area (VTA) is involved in adaptive reward and motivation processing and is composed of dopamine (DA) and GABA neurons. Defining the elements regulating activity and synaptic plasticity of these cells is critical to understanding mechanisms of reward and addiction.
Sep 14, 2023 · The brain's reward system is a network of structures responsible for pleasure, motivation, and reinforcement learning. Central to this system are the Ventral Tegmental Area (VTA) and the Nucleus Accumbens (NAc). When a rewarding stimulus is perceived, dopamine is released from the VTA, acting on the NAc, leading to feelings of pleasure.
