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4 days ago · The striatum (a collective term for the caudate nucleus and putamen; see Figure 38–1), subthalamic nucleus, and substantia nigra pars compacta/ventral tegmental area are the three major input nuclei of the basal ganglia, receiving signals directly and indirectly from structures distributed throughout the neuraxis (Figure 38–2). + +
18 hours ago · We looked at the ventral tegmental area because it is where cell bodies of mesocorticolimbic dopamine neurons are located. We found significant effects of age (t = 5.50, q < 0.0001) and genotype (t = −3.53, q = 0.01; Figure 1). We also looked at the orbital and insular subregions of the prefrontal cortex, which also receive mesocortical ...
Apr 3, 2024 · The mesopontine rostromedial tegmental nucleus: A structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta. J Comp Neurol. 2009 ...
Apr 4, 2024 · While dopaminergic neurons in both the substantia nigra and the ventral tegmental area have pacemaker activity (spontaneous rhythmic firing), only that of substantia nigra dopaminergic neurons is ...
Apr 3, 2024 · Mesolimbic dopamine (DA) neurotransmission from ventral tegmental area (VTA) DAergic neurons innervating the ventral striatum is engaged by exposure to social cues both in humans 8 and animal ...
3 days ago · The brain stem includes the medulla and pons, located ventral to the cerebellum. In addition to housing essential ascending and descending tracts, the brain stem contains nuclei that are essential for maintenance of life. As a result of the relatively tight packaging of numerous ascending and descending tracts, as well as nuclei, within the ...
Apr 8, 2024 · For example, mDA neurons of the substantia nigra pars compacta (SNc) are mainly associated with controlling motor functions. In contrast, those in the ventral tegmental area (VTA) and retrorubral field (RRF) have been associated more strongly with motivation, learning, and cognition (Björklund and Dunnett, 2007). Notably, mDA neurons are also ...
