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  1. General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.

    • Table 1

      Given the wide heterogeneity of phenotypes and of the...

    • Mcmdm-1Vwd

      Introduction. von Willebrand factor (VWF) is a multimeric...

  2. There are many treatment options available for patients with von Willebrand disease and heavy menstrual bleeding, including hormonal and nonhormonal therapies. A multidisciplinary approach to management, which involves obstetrician–gynecologists and hematologists, results in optimal treatment outcomes.

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  4. Jan 10, 2022 · von Willebrand disease (VWD) disproportionately affects women because of the potential for heavy menstrual bleeding (HMB), delivery complications, and postpartum hemorrhage (PPH). To systematically synthesize the evidence regarding first-line management of HMB, treatment of women requiring or desiring neuraxial analgesia, and management of PPH.

  5. May 20, 2019 · The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.

    • Giancarlo Castaman, Paula D. James
    • 2019
  6. Reynen E, James P. Von Willebrand disease and pregnancy: a review of evidence and expert opinion. Semin Thromb Hemost . 2016;42(7):717-723. Stoof SC, van Steenbergen HW, Zwagemaker A, et al. Primary postpartum haemorrhage in women with von Willebrand disease or carriership of haemophilia despite specialised care: a retrospective survey.

  7. Nov 5, 2020 · Carriers of hemophilia A (HA) or hemophilia B (HB) and women suffering from von Willebrand disease (VWD) have an increased risk for bleeding during pregnancy and delivery. Management of these women concerns not only managing the bleeding tendency of the mother, but also that of the child with a potential bleeding disorder.

  8. Feb 14, 2024 · Pregnancy and childbirth. With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. A woman who has VWD should be monitored closely throughout her pregnancy by her doctors. It is important for a woman's health care providers to be aware that she has VWD so that plans can be made for a ...

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    related to: von willebrand in pregnancy treatment pictures of women
  2. Visit VONVENDI® [von Willebrand factor (Recombinant)] site to view clinical study results.

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