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Morbilliform drug eruption is a form of allergic reaction. It is mediated by cytotoxic T-cells and classified as a Type IV immune reaction. The target of attack may be drug, a metabolite of the drug, or a protein bonded to the drug. Inflammation follows the release of cytokines and other effector immune cells.
Mar 13, 2019 · The term “morbilliform” connotes a measles-like: the rash of measles is classically described as having macules that are 3 to 4 mm in size that coalesce. MDE is usually itchy. The eruption usually begins on the trunk and upper extremities and progresses caudally. It is usually symmetric.
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Jan 12, 2023 · Exanthematous (maculopapular) drug eruption, also called morbilliform (measles-like) drug-induced exanthem, is the most common drug hypersensitivity reaction [ 1,2 ]. It is characterized by a disseminated, and occasionally generalized, symmetric eruption of erythematous macules and/or papules ( picture 1A-B) that occur approximately one to two ...
Mar 8, 2021 · Exanthematous (morbilliform) drug eruptions are the most common type of adverse drug reaction. Thought to be delayed-type, T cell-mediated immune reaction. Characterized by erythematous macules and papules coalescing into patches and plaques without secondary change that predominantly involve the trunk and proximal extremities.
May 1, 2024 · 6 min read. What Is a Morbilliform Rash? A morbilliform rash is any rash that looks a lot like measles. The word “morbilliform” means measles-like. Sometimes dermatologists call them...
Apr 26, 2022 · Morbilliform drug eruption is a rash that develops because of an adverse reaction to a drug. Antibiotics are the usual trigger, but many drugs can trigger this allergic reaction. It may...
Jun 1, 2023 · Morbilliform drug rash, also called exanthematous or maculopapular drug eruption, is the most common, classically presenting with an erythematous maculopapular rash 1 to 2 weeks after a drug exposure. Urticarial rash, the second most common, presents as annular, pruritic, migratory plaques usually within hours of initial drug exposure. 2.
