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Orthonairovirus is a genus of viruses in the family Nairoviridae of the order Bunyavirales that include viruses with circular, negative-sense single stranded RNA. [1] It got its name from the Nairobi sheep disease that affects the gastrointestinal tracts of sheep and goats. [1] The vast majority, and perhaps all viruses in this genus are tick ...
- Orthonairovirus
- Nairoviridae
Family: Nairoviridae Genus: Orthonairovirus Distinguishing features. There are 51 distinct viruses currently assigned to the genus Orthonairovirus.These viruses typically infect specific argasid or ixodid ticks, which transmit them to small vertebrates (birds and mammals) that in turn then server as sources for tick infection.
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Feb 18, 2021 · The genus Orthonairovirus, which is part of the family Nairoviridae, includes the important tick-transmitted pathogens Crimean–Congo hemorrhagic fever virus and Nairobi sheep disease virus, as ...
- Jun Ma, Jun Ma, Xiao-Long Lv, Xu Zhang, Shu-Zheng Han, Ze-Dong Wang, Liang Li, He-Ting Sun, Li-Xin M...
- 2021
Jun 27, 2021 · Nairobi sheep disease orthonairovirus (NSDV) is a zoonotic tick-borne arbovirus, which causes severe gastroenteritis in small ruminants. To date, the virus is prevalent in East Africa and Asia. However, due to climate change, including the spread of transmitting tick vectors and increased animal movements, it is likely that the distribution ...
- Julia Hartlaub, Benjamin Gutjahr, Christine Fast, Ali Mirazimi, Markus Keller, Martin H. Groschup
- 10.3390/v13071250
- 2021
- Viruses. 2021 Jul; 13(7): 1250.
The Crimean–Congo hemorrhagic fever orthonairovirus (CCHFV) is a member of the genus Orthonairovirus, family Nairoviridae of RNA viruses. The virions are 80–120 nanometers (nm) in diameter and are pleomorphic. There are no host ribosomes within the virion. Each virion contains three distinct RNA sequences, which together make up the viral ...
Mar 29, 2023 · Four of nine Orthonairovirus genogroups can infect humans, with Crimean-Congo hemorrhagic fever virus infections displaying case fatality rates up to 40%. Here, we discover and describe a novel Orthonairovirus as Cencurut virus (CENV). CENV was detected in 34 of 37 Asian house shrews ( Suncus murinus) sampled in Singapore and in a nymphal ...
Jul 13, 2021 · Dugbe orthonairovirus (prototype strain IBAR1792) and Nairobi sheep disease orthonairovirus (Ganjam prototype strain IG619) were a kind gift from the World Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, USA. All viruses were grown on SW13 cells, which were also provided by Ali Mirazimi.
