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Howard Walter Florey (1898–1968) and Ernst Boris Chain (1906–1979) were the scientists who followed up most successfully on Alexander Fleming’s discovery of penicillin, sharing with him the 1945 Nobel Prize in Physiology or Medicine.
Howard Walter Florey, Baron Florey (born Sept. 24, 1898, Adelaide, Australia—died Feb. 21, 1968, Oxford, Eng.) was an Australian pathologist who, with Ernst Boris Chain, isolated and purified penicillin (discovered in 1928 by Sir Alexander Fleming) for general clinical use.
- The Editors of Encyclopaedia Britannica
Howard Walter Florey, Baron Florey, OM FRS FRCP (/ ˈ f l ɔːr i /; 24 September 1898 – 21 February 1968) was an Australian pharmacologist and pathologist who shared the Nobel Prize in Physiology or Medicine in 1945 with Ernst Chain and Sir Alexander Fleming for his role in the development of penicillin.
- Howard Walter Florey, 24 September 1898, Adelaide, South Australia
- Discovery of penicillin
- 2, including Charles du Vé
Feb 23, 2021 · Nearly ten years later in 1937, while investigating microorganisms and the substances they produced, Howard Florey and Ernst Chain uncovered Fleming’s research and assembled a team of scientists to work solely on the 'Penicillin Project'.
Sir Ernst Boris Chain was a German-born British biochemist who, with pathologist Howard Walter Florey, isolated and purified penicillin (which had been discovered in 1928 by Sir Alexander Fleming) and performed the first clinical trials of the antibiotic.
- The Editors of Encyclopaedia Britannica
Chain and Florey discovered how to isolate and concentrate the germ-killing agent in penicillin. For this research, Chain, Florey, and Fleming received the Nobel Prize in 1945.
Large-scale production of penicillin was developed by Florey and German-born British biochemist Ernst B. Chain more than a decade later. Florey was born in Adelaide, South Australia, on September 26, 1898, the youngest of five children. His father was a manager for a shoe manufacturing company.
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