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Oct 18, 2019 · The nucleus accumbens (NAc) is a subcortical brain structure known primarily for its roles in pleasure, reward, and addiction. Despite less focus on the NAc in pain research, it also plays a large role in the mediation of pain and is effective as a source of analgesia.
The Nucleus Accumbens: An Interface Between Cognition, Emotion, and Action. Stan B. Floresco 1. View Affiliations. Vol. 66:25-52 (Volume publication date January 2015) https://doi.org/10.1146/annurev-psych-010213-115159. First published as a Review in Advance on September 17, 2014. © Annual Reviews. info Info. list Sections. PDF. build Tools.
The NAc is a central component of the basal ganglia that is known as the pleasure center of the brain. The NAc receives dopaminergic projections from the VTA and glutamatergic projections from the medial PFC and plays an important role in reward-related phenomena ( Kalivas and Volkow, 2005 ).
There is increasing interest among functional neurosurgeons in the potential for novel therapies to impact upon diseases beyond movement disorders and pain. A target of increasing interest is the nucleus accumbens (NAc), which has long been studied as a key brain region mediating a variety of behavi ….
The ventral striatum, including the nucleus accumbens (NAcc), is a major substrate involved in reward ( Marche et al. 2017 ).
Mar 19, 2015 · The nucleus accumbens (NAc) is a major component of the ventral striatum and has long been thought to be a key structure involved in mediating motivational and emotional processes, the limbic-motor interface, and the effects of certain psychoactive drugs.
Jan 1, 2022 · The nucleus accumbens (NAc), a part of ventral striatum, is mostly involved with reward, motivation, satisfaction, motor function, and learning. NAc itself is made up of two anatomical components, a central core and an outer shell and both has different contributions to the function of nucleus accumbens.
