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May 14, 2021 · Sepsis is a life-threatening condition and a global disease burden. Today, the heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated host response to infection, with renewed emphasis on immune pathophysiology.
Jan 18, 2024 · Sepsis results when the response to infection becomes generalized and involves normal tissues remote from the site of injury or infection. The pathophysiology of sepsis and mechanisms of multiple organ system dysfunction are reviewed here.
Mar 21, 2019 · Sepsis is a medical emergency that describes the body’s systemic immunological response to an infectious process that can lead to end-stage organ dysfunction and death.
Feb 10, 2023 · Sepsis is a serious condition in which the body responds improperly to an infection. The infection-fighting processes turn on the body, causing the organs to work poorly. Sepsis may progress to septic shock.
May 23, 2016 · Sepsis, severe sepsis, and septic shock represent increasingly severe systemic inflammatory responses to infection. Sepsis is common in the aging population, and it disproportionately affects patients with cancer and underlying immunosuppression.
Jul 7, 2021 · INTRODUCTION. Medicine has made fantastic strides over the past century. Our intricate knowledge of disease has been spearheaded by amazing advances in laboratory techniques that allow us to identify and instigate changes at the molecular level.
Jan 9, 2003 · Advances in unraveling the pathophysiology and genetic basis for the host response to sepsis have changed the prevailing understanding of the syndrome, and several therapies have demonstrated...
Dec 2, 2022 · Immunopathophysiology of human sepsis. Summary. Sepsis is an ill-defined syndrome yet is a leading cause of morbidity and mortality worldwide. The most recent consensus defines sepsis as life-threatening organ dysfunction caused by a dysregulated host response to infection.
Sepsis is a life-threatening medical emergency caused by your body’s overwhelming response to an infection. Without urgent treatment, it can lead to tissue damage, organ failure and death.
Jul 19, 2024 · Sepsis is a person’s overwhelming or impaired whole-body immune response to an insult —an infection or an injury to the body, or something else that provokes such a response. Sepsis occurs unpredictably and can progress rapidly. In the worst cases, blood pressure drops, the heart weakens, and the patient spirals toward septic shock.
