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  1. Ulrich was born in 1413, the youngest child of Count Eberhard IV and his wife Henriette, Countess of Mömpelgard. [5] Eberhard died unexpectedly of illness on 2 July 1419, while Ulrich and his older brother Ludwig were both minors. [6] Consequently, Henriette became their guardian, together with a regency council of 32 Württembergers.

  2. Oct 10, 2020 · Since DNA methylation modifies the potential function and physical properties of the base, changes in methylation could also influence genome integrity and cancer by altering various processes either directly through mutations involving base changes and coding outcomes or more broadly through the DDR and DNA repair.

    • Anusha Sriraman, Turja K Debnath, Blerta Xhemalce, Kyle M Miller
    • 10.1042/EBC20200009
    • 2020
    • 2020/10/10
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  4. Apr 23, 2019 · Abstract. DNA methylation represents a fundamental epigenetic mark that is associated with transcriptional repression during development, maintenance of homeostasis, and disease. In addition to methylation-sensitive PCR and targeted deep-amplicon bisulfite sequencing to measure DNA methylation at defined genomic loci, numerous unsupervised ...

    • Benjamin D. Singer
    • 10.1165/rcmb.2019-0150TR
    • 2019
    • 2019/10
  5. Mar 18, 2024 · Published: 18 March 2024. The impact of DNA methylation on CTCF-mediated 3D genome organization. Ana Monteagudo-Sánchez, Daan Noordermeer & Maxim V. C. Greenberg. Nature Structural &...

  6. Dec 13, 2019 · DNA methylation is a major epigenetic mechanism that involves the transfer of a methyl group to the C5 carbon residues (5mC) of cytosines that is mediated by a family of DNA methyltransferases. 24 ...

    • Wanxue Xu, Mengyao Xu, Longlong Wang, Wei Zhou, Rong Xiang, Yi Shi, Yunshan Zhang, Yongjun Piao
    • 2019
  7. Jul 3, 2023 · This demonstrates the potential of the INTEND integration method to uncover connections between DNA methylation and the regulation of gene expression, for both proximal and distal methylation sites.

  8. Apr 30, 2021 · Research interest in genetic impacts on DNA methylation variation is especially relevant in context of methylome changes observed in disease [ 16, 21 – 23 ], alongside results from genome-wide association studies (GWASs).

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